Rome’s main cruise season is from April through October when cruises of the Mediterranean and the Greek Islands are popular. Some ships sail the region year-round, but fewer itineraries are offered in the winter and early spring. Most trips are between seven and 21 days in length and call at ports in a variety of countries.
As temperatures spike in the region during the summer months, tourist traffic also increases. Visitors can avoid some of the heat and crowds by traveling during the shoulder seasons in the spring (April and May) or fall (September and October). The temperatures are still comfortable during these months -- the high temperature in Rome is above 65 degrees -- but the number of people visiting the sites and packing the beaches will be greatly reduced.
Visitors who don't mind a bit of a chill might enjoy an off-season cruise during the winter months. Temperatures in the Mediterranean rarely drop below freezing, so it's still a welcome alternative to frigid temperatures and snow.